Core-binding factor alpha 1
WebThe alpha-subunit binds DNA as a monomer, and appears to have a role in the development of normal hematopoiesis. CBF is a nuclear protein expressed in numerous tissue types, except brain and heart; highest levels have been found to occur in thymus, bone marrow and peripheral blood. WebCore Binding Factor Alpha 1 Subunit Core Binding Factor alpha Subunits Humans Neoplasm Proteins* Osteoblasts / cytology Osteoblasts / physiology* Osteogenesis / …
Core-binding factor alpha 1
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WebThe present disclosure provides compositions and methods for targeting a Core Binding Factor, β-subunit:Myosin Heavy Chain 11 (CBFβ:MYH11) antigen to, for example, prevent or manage relapse of Acute Myeloid Leukemia (AML). Also provided are polynucleotides and transgene constructs encoding binding proteins, such as a T cell receptor or a ... WebEIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex.
National Center for Biotechnology Information WebMar 31, 2024 · A core enhancer-binding activity also appears to be restricted to XP nuclei. Here we describe the properties of a factor, purified approximately 100,000-fold from pancreas nuclei, which displays core enhancer-binding activity. It is not identical to previously characterized factors and is termed exocrine pancreas transcription factor 1 …
• Hart SM, Foroni L (2003). "Core binding factor genes and human leukemia". Haematologica. 87 (12): 1307–23. PMID 12495904. • Bae SC, Takahashi E, Zhang YW, et al. (1995). "Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain". Gene. 159 (2): 245–8. doi:10.1016/0378-1119(95)00060-J. PMID 7622058. WebOct 1, 2010 · Foxo1, a novel regulator of osteoblast differentiation and skeletogenesis Skeletogenesis depends on the activity of bone-forming cells derived from mesenchymal …
WebFeb 21, 2007 · Core Binding Factor Alpha 1 Subunit / genetics* Core Binding Factor Alpha 2 Subunit / genetics* Core Binding Factor beta Subunit / metabolism DNA / …
WebFormalin-fixed and paraffin embedded human colitis tissue labeled with Anti-TNF-alpha Polyclonal Antibody, Unconjugated (bs-0077R) 1:300 followed by conjugation to the secondary antibody and DAB staining. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 for 90 min at 37°C. Predicted band 17 kD, 26 kD. they\\u0027d f8Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the RUNX2 gene. RUNX2 is a key transcription factor associated with osteoblast differentiation. It has also been suggested that Runx2 plays a cell proliferation regulatory role in cell … they\u0027d faWebThe differentiation from multipotent hematopoietic stem cells (HSC) to mature and functional blood cells requires the finely tuned regulation of gene expression at each stage of … they\u0027d f4WebNov 2, 2001 · Core-binding factor subunit alpha-1 ( CBF-alpha-1) Oncogene AML-3 Osteoblast-specific transcription factor 2 ( OSF-2) Polyomavirus enhancer-binding protein 2 alpha A subunit ( PEA2-alpha A; PEBP2-alpha A) More alternative names Gene names Name Runx2 Synonyms Aml3, Cbfa1, Osf2, Pebp2a Organism names Organism Mus … they\u0027d f7WebAbcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing. they\u0027d f8WebOct 24, 2024 · In the mouse, PEBP2 (also known as core-binding factor) is a heterodimer consisting of 2 polypeptides: alpha, the DNA-binding subunit, and beta (PEBP2B; 121360 ), which associates with the alpha subunit and enhances its affinity for DNA. Zhang et al. (1997) cloned the PEBP2A gene. they\\u0027d f5WebMar 13, 2024 · Core Binding Factor Alpha 1 Subunit IL6 protein, human Interleukin-6 MIRN204 microRNA, human MicroRNAs RNA, Small Interfering RUNX2 protein, human … they\\u0027d fa