WebAug 17, 2024 · The NDC80 complex, which consists of NDC80, SPC25, and two other members, contributes to the microtubule–kinetochore attachment and spindle assembly checkpoint in mitosis. SPC25 is additionally required for chromosome alignment, spindle formation, and proper spindle checkpoint signaling during oocyte meiosis [ 99 ]. WebGroup of answer choices the completion of DNA replication attachment of spindle fibers to kinetochores cell size ALL OF THESE the presence of DNA damage Expert Answer 100% (1 rating) M- Checkpoint It is also known as the Spindle checkpoint . This is the place where the cell examines or checks w … View the full answer Previous question Next question
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WebWhat is the purpose of cell-cycle checkpoints, such as the DNA-damage checkpoint for the spindle-attachment checkpoint'? B. You isolate mutant cells defective in the DNA-damage checkpoint, but you find that under normal laboratory conditions, the mutant cells grow and divide at the same rate as wild-type cells. pushprojectco
Spindly attachments
WebOverview of Spindle Assembly Checkpoint: This is a key event in M-phase and there is a cascade of events that must take place to trigger the onset of anaphase. When cells "sense" that all sister chromatids have their proper microtubule attachments in the spindle, they activate this cascade of events. WebThe spindle assembly checkpoint (SAC) is a surveillance mechanism that promotes accurate chromosome segregation in mitosis. The checkpoint senses the attachment … WebAug 18, 2024 · For faithful chromosome segregation, the formation of stable kinetochore-microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined. Here, we show that polo-like kinase 1 (Plk1), which is instrumental in … push program stroke